The Pharma 24 dedicated TSG provides maximum process flexibility through many features: Horizontally split extruder barrel for easy access and cleaning Easy-to-operate clamp shell design Removable top and bottom liners, made from pharma grade steel Main port with availability for 5 additional multi-purpose, top feed/injection ports Flexible base for stand-alone operation or easy adaption to existing downstream equipment at an existing production site Optimal design for challenging environments The Pharma 24 TSG can set up with an optional design to operate in challenging environments. The liquid temperature control of the TSG barrel ranges from 20°C to 80°C without any electrical heating. The instrument can be set up with 1-3 cooling zones when intensive cooling of the barrel is necessary. Maximum control and connectivity For the best possible process control, sensors such as temperature sensors or optional process analytical technology (PAT) sensors can be used with the Pharma 24 TSG. The Pharma 24 TSG is operated from a touch panel on a movable frame, and TCP/IP can be used to integrate it into an existing overarching IT architecture. Maximum user control is delivered via five different user levels with password protection and comprehensive reporting.
Pharma 24 Twin-Screw Granulator
The Thermo Scientific™ Pharma 24 Twin-Screw Granulator (TSG) is a dedicated system for wet and dry granulation processes. It can be used as a stand-alone instrument or integrated into a modular, continuous manufacturing line that spans from raw materials to final tableting. Such flexibility minimizes scale-up risks.
| Speed Range |
10 to 1000 rpm |
|---|---|
| Electrical Requirements |
3 x 400 V, N, PE, 50/60 Hz @32 A |
| Relative Humidity |
Max. 80% at 31°C (50% at 40°C) |
| Throughput |
70 kg/h (depending on formulation) |
| Torque per Shaft |
18 Nm |
| Screw Diameter (Metric) |
24 mm |
| Heating Zones |
1 cooling zone standard. 1-2 additional cooling zones optional for up to 3 total cooling zones. |
| Height (Metric) |
Extruder: 550 mm, Cabinet: 300 mm |
| Length (Metric) |
Extruder: 2000 mm, Cabinet: 1000 mm |
| Width (Metric) |
Extruder: 320 mm, Cabinet: 1200 mm |
| Temperature Range (Metric) |
Operating temperature range 10 to 80 °C, External temperature range (chiller) 5 °C to 0 °C (below 10 °C eventually condensation) |
| Barrel |
4 segments for top / bottom half |
| Temperature Control |
In/Output: G 1/2 in. |
| Weight (Metric) |
Extruder: 265 kg, Cabinet: 180 kg |
| Unit Size |
Each |
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