sold under the trade names Subutex,Buprenex,Temgesic and Suboxone, which contain Buprenorphine HCl alone or in combination with Naloxone HCl.Therapeutically, Buprenorphine is used as a substitution treatment for opioid addicts. Substitution treatment is a form of medical care offered to opiate addicts (primarily heroin addicts) based on a similar or identical substance to the drug normally used 1.Application Buprenorphine (BUP) Single Drug Test Cassette is a rapid urine drug screening test that can be performed without the use of an instrument. Buprenorphine is a potent analgesic often used in the treatment of opioid addiction.The drug is sold under the trade names Subutex,Buprenex,Temgesic and Suboxone, which contain Buprenorphine HCl alone or in combination with Naloxone HCl.Therapeutically, Buprenorphine is used as a substitution treatment for opioid addicts. Substitution treatment is a form of medical care offered to opiate addicts (primarily heroin addicts) based on a similar or identical substance to the drug normally used. 2.Principle Buprenorphine (BUP) Drug Test Device is an immunoassay based on the principle of competitive binding.Drugs which may be present in the urine specimen compete against the drug conjugate for binding sites on the antibody. One Step Buprenorphine Drug Test Device is a rapid urine drug screening test that can be performed without the use of an instrument.During testing,a urine specimen migrates upward by capillary action. Buprenorphine, if present in the urine specimen below 10 ng/mL,will not saturate the binding sites of antibody-coated particles in the test. The antibody-coated particles will then be captured by immobilized Buprenorphine conjugate and a visible colored line will show up in the test line region. The colored line will not form in the test line region if the Buprenorphine level exceeds 10 ng/mL because it will saturate all the binding sites of anti-Buprenorphine antibodies. A drug-positive urine specimen will not generate a colored line in the test line region because of drug competition,while a drug-negative urine specimen or a specimen containing a drug concentration lower than the cut-off will generate a line in the test line region. To serve as a procedural control,a colored line will always appear at the control line region,indicating that proper volume of specimen has been added and membrane wicking has occurred.